Kareem Esmail is a certified coach specializing in positive psychology, an entrepreneur, and an influential Egyptian figure in the mental health and self-development space. Before dedicating himself to this field, Esmail was a professional soccer player for 15 years, even playing for the Egyptian U-20 national team. After a significant career shift, he pursued coaching and personal development, earning prestigious international certifications, including as an Associated Certified Coach (ACC) from the International Coach Federation (ICF) and a Certified Strengths Coach from Gallup. In August 2012, he launched his YouTube channel, which has become a primary platform for his inspirational content that blends scientific principles of positive psychology with religious teachings and philosophy in an accessible, practical style. Esmail is the Founder and CEO of Mental Health Hub (formerly Mental Health MENA), an organization dedicated to promoting mental health awareness across the Middle East and North Africa through specialized courses and workshops. He also hosts the popular podcast "Behodooa ma' Kareem Esmail" (Calmly with Kareem Esmail), where he discusses various topics aimed at improving listeners' psychological well-being. Through his work, Kareem has trained and spoken to over 100,000 individuals at numerous conferences, universities, and major events.

Kareem Esmail founded Mental Health Hub, a leading platform providing specialized mental health services and courses in Arabic. The organization aims to bridge a critical gap in the MENA region, making psychological awareness and practical tools accessible to a wider audience to improve their quality of life. In 2020, he published his bestselling book, "Estiraha Nafsia" (A Soulful Rest). The book was highly successful, becoming one of the most prominent Arabic titles in psychology and self-development. It combines science, religion, and philosophy to offer readers a new perspective on achieving better mental health and coping with life's pressures. Esmail has built an impactful digital presence across multiple platforms, delivering educational and inspirational content to millions of followers. Through his YouTube channel and his podcast, "Behodooa ma' Kareem Esmail," he offers deep-dive sessions and discussions on topics like self-esteem, recovering from burnout, and building healthy relationships, establishing himself as a trusted voice in his field.

No verified information was found regarding his formal academic background. He is a certified coach by the International Coach Federation (ICF) and a Gallup-Certified Strengths Coach.