Sameh Hussein is an Egyptian actor and director, born in the Shubra district of Cairo on December 16, 1975. He has built a rich and diverse artistic career, establishing himself as one of Egypt's most prominent comedy stars. Hussein uniquely combined legal studies, earning a law degree from Ain Shams University, with his passion for the arts, graduating from the Theater Department at Helwan University and further honing his skills at the Artistic Creativity Center of the Cairo Opera House. His career began with minor roles in the late 1990s, but his major breakthrough came in 2006 with the role of "Ramzy" in the popular sitcom "Ragel we Set Settat" (A Man and Six Women). This role brought him widespread fame among Egyptian and Arab audiences. Following this success, he transitioned to leading roles, starring in successful series like "Aboudah Marka Mosagalah" (2009) and "Al Less Wal Kitab" (The Thief and the Book) (2010), where he skillfully portrayed twin characters. Hussein also showed a keen interest in children's entertainment, founding a production company through which he created the animated series "Captain Azzouz." His success extends beyond television to cinema, with notable films including "H Dabbour" (2008), "30 February" (2012), and "Kalby Dalily" (2013). He also maintains a strong presence in theater, with acclaimed performances in plays like "Ana Al Ra'ees" (I am the President) (2015), "Al Motafa'el" (The Optimist) (2019), and "Helm Gameel" (A Beautiful Dream) (2022).

Sameh Hussein achieved a major breakthrough with his role as "Ramzy" in the sitcom "Ragel we Set Settat," for which he won the Best Rising Actor award at the Cairo Arab Media Festival in 2008. This role was a pivotal turning point in his career and a primary reason for his widespread popularity. His series "Al Less Wal Kitab" (The Thief and the Book) (2010) received widespread critical and audience acclaim, winning the Golden Award for Best Social Series at the Jordan Arab Media Festival. Hussein also won the Dear Guest Award for Best TV Comedian for his role in the series, solidifying his status as a leading comedy-drama star. He has received several prestigious awards for his work, including the Dear Guest Award and the ART Award for Best Comedian for the series "Aboudah Marka Mosagalah" in 2009. In recognition of his artistic career, he was granted the Golden Visa by the United Arab Emirates in 2025.

Sameh Hussein studied at the Faculty of Law at Ain Shams University. He also holds a Bachelor of Arts in Theater (Acting and Directing) from Helwan University. Additionally, he is a graduate of the first class of the Artistic Creativity Center at the Egyptian Opera House.